Lecture Description
Introduction : Orthodontic appliances hamper effective oral hygiene with heavy accumulation of dental plaques in the area, leading to the negative consequences such as decalcification of enamel surface (white spot lesions), caries, as well as gingival inflammation. So far, no effective methods could control the dental plaque in orthodontic patients. Thus, a novel way to inhibit bracket-induced plaque formation has been developed and will be presented here.
Discussion : First, several chemical compounds that have anti-plaque formation effect were discovered based on the previous finding in the lab and then were formulated into toothpaste with strong inhibitory effect against bracket-induced plaque in vitro. Furthermore, building on the strong preliminary data, a randomized, double-blinded, placebo-controlled, pilot clinical study was conducted to evaluate the safety and efficacy of this newly formulated toothpaste in vivo. The new formula is safe without adverse event during the clinic study.
Conclusion : The clinic results suggested that this novel formulation could potentially manage microbial associated complications in orthodontic patients.
October 28-30, 2022 ¡¤ COEX, Seoul, Korea